4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE

4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE - Names and Identifiers

Name	1-(4-CHLOROPHENYL)-4,4,4-TRIFLUORO-1,3-BUTANEDIONE
Synonyms	AKOS B006855 AKOS MSC-0334 ART-CHEM-BB B006855 3-(4-CHLOROBENZOYL)-1,1,1-TRIFLUOROACETONE 1-(4-CHLOROPHENYL)-4,4,4-TRIFLUORO-1,3-BUTANEDIONE 4-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2,4-BUTANEDIONE 1-(P-CHLOROPHENYL)-4,4,4-TRIFLUORO-1,3-BUTANEDIONE 1-(4-CHLOROPHENYL)-4,4,4-TRIFLUOROBUTANE-1,3-DIONE 4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE (3Z)-4-(4-chlorophenyl)-1,1,1-trifluoro-4-hydroxybut-3-en-2-one
CAS	18931-60-7
InChI	InChI=1/C10H6ClF3O2/c11-7-3-1-6(2-4-7)8(15)5-9(16)10(12,13)14/h1-5,15H/b8-5-

4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE - Physico-chemical Properties

Molecular Formula	C10H6ClF3O2
Molar Mass	250.6
Density	1.396±0.06 g/cm3(Predicted)
Melting Point	60-64 °C (lit.)
Boling Point	292.4±35.0 °C(Predicted)
Flash Point	123.6°C
Vapor Presure	0.00176mmHg at 25°C
pKa	5.35±0.25(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.516

4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
Hazard Class	IRRITANT

4,4,4-TRIFLUORO-1-(4-CHLOROPHENYL)-1,3-BUT ANEDIONE - Introduction

1-(4-CHLOROPHENYL)-4,4,4-TRIFLUORO-1, 3-butylenedione, often abbreviated as CFA(ChloroPhenyl TrifluoroAcetone), has the following properties:

1. Appearance: colorless or light yellow liquid.
2. Density: 1.49 g/mL.
3. Melting point:-28 ° C.
4. Boiling Point: 135-137 C.
5. Solubility: soluble in organic solvents, such as ethanol, ether and petroleum ether.

The uses of CFA include but are not limited to the following:
1. As reagents and intermediates in organic synthesis, it can be used to synthesize organic compounds such as drugs, hormones, pesticides, etc.
2. Used as an additive in surfactants, coatings and inks, with the effect of increasing viscosity and solubility.
3. For the synthesis and modification of photovoltaic materials, electronic materials and polymer materials.
4. Used as a heavy metal chelating agent in the pharmaceutical field, with anti-tumor and anti-viral activity.

CFA can be prepared by the following methods:
Tetrafluoroacetic anhydride reacts with P-chlorobenzaldehyde to generate 1-(4-CHLOROPHENYL)-4,4,4-TRIFLUORO-1, 3-butylenedione.

regarding the safety information of CFA, there are the following points to note:
1. CFA is irritating and corrosive. Contact with skin, eyes and respiratory tract will cause irritation and injury. Appropriate protective equipment should be worn for operation.
2. When using or storing CFA, keep away from fire and high temperature, and avoid contact with strong oxidants.
3. If accidental leakage or contact with CFA, rinse immediately with plenty of water and seek medical treatment.
4. When using CFA in a laboratory or industrial environment, you should follow the safety operating procedures and be equipped with corresponding safety equipment.

Last Update：2024-04-10 22:43:14